Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers

Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers

Abstract Background Early diagnosis of rheumatoid arthritis (RA) is crucial to providing effective therapy and often hampered by unspecific clinical manifestations. Elevated levels of extracellular circulating DNA (cirDNA) in patients with autoimmune disease were found to be associated with etiopath...

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Bibliographic Details
Main Authors: Elena Rykova, Aleksey Sizikov, Dirk Roggenbuck, Oksana Antonenko, Leonid Bryzgalov, Evgeniy Morozkin, Kseniya Skvortsova, Valentin Vlassov, Pavel Laktionov, Vladimir Kozlov
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Circulating nuclear DNA
Mitochondrial DNA
Real-time PCR
Antibodies to citrullinated protein/peptide
Rheumatoid factor
Online Access:http://link.springer.com/article/10.1186/s13075-017-1295-z

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http://link.springer.com/article/10.1186/s13075-017-1295-z

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