Dalcetrapib and anacetrapib increase apolipoprotein E-containing HDL in rabbits and humans

Dalcetrapib and anacetrapib increase apolipoprotein E-containing HDL in rabbits and humans

The large HDL particles generated by administration of cholesteryl ester transfer protein inhibitors (CETPi) remain poorly characterized, despite their potential importance in the routing of cholesterol to the liver for excretion, which is the last step of the reverse cholesterol transport. Thus, th...

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Bibliographic Details
Main Authors: Mathieu R. Brodeur, David Rhainds, Daniel Charpentier, Marie Boulé, Téodora Mihalache-Avram, Mélanie Mecteau, Geneviève Brand, Valérie Pedneault-Gagnon, Annik Fortier, Eric J. Niesor, Eric Rhéaume, Cyrille Maugeais, Jean-Claude Tardif
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Lipid Research
Subjects:
CETP
cholesteryl ester transfer protein inhibitors
apolipoprotein composition
low-density lipoprotein receptor
atorvastatin
dal-PLAQUE-2 study
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001493

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http://www.sciencedirect.com/science/article/pii/S0022227522001493

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