Large-scale voltage imaging in behaving mice using targeted illumination

Summary: Recent improvements in genetically encoded voltage indicators enabled optical imaging of action potentials and subthreshold transmembrane voltage in vivo. To perform high-speed voltage imaging of many neurons simultaneously over a large anatomical area, widefield microscopy remains an essen...

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Bibliographic Details
Main Authors: Sheng Xiao, Eric Lowet, Howard J. Gritton, Pierre Fabris, Yangyang Wang, Jack Sherman, Rebecca A. Mount, Hua-an Tseng, Heng-Ye Man, Christoph Straub, Kiryl D. Piatkevich, Edward S. Boyden, Jerome Mertz, Xue Han
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221012323