Cofilin activation in peripheral CD4 T cells of HIV-1 infected patients: a pilot study
<p>Abstract</p> <p>Cofilin is an actin-depolymerizing factor that regulates actin dynamics critical for T cell migration and T cell activation. In unstimulated resting CD4 T cells, cofilin exists largely as a phosphorylated inactive form. Previously, we demonstrated that during HIV...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | Retrovirology |
Online Access: | http://www.retrovirology.com/content/5/1/95 |