Cofilin activation in peripheral CD4 T cells of HIV-1 infected patients: a pilot study

<p>Abstract</p> <p>Cofilin is an actin-depolymerizing factor that regulates actin dynamics critical for T cell migration and T cell activation. In unstimulated resting CD4 T cells, cofilin exists largely as a phosphorylated inactive form. Previously, we demonstrated that during HIV...

Full description

Bibliographic Details
Main Authors: Barrett Tracey, Liu Juan, Wang Weifeng, Yu Dongyang, Yoder Alyson, Wu Yuntao, Wheeler David, Schlauch Karen
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/95