Cell type determination for cardiac differentiation occurs soon after seeding of human-induced pluripotent stem cells

Abstract Background Cardiac differentiation of human-induced pluripotent stem (hiPS) cells consistently produces a mixed population of cardiomyocytes and non-cardiac cell types, even when using well-characterized protocols. We sought to determine whether different cell types might result from intrin...

Full description

Bibliographic Details
Main Authors: Connie L. Jiang, Yogesh Goyal, Naveen Jain, Qiaohong Wang, Rachel E. Truitt, Allison J. Coté, Benjamin Emert, Ian A. Mellis, Karun Kiani, Wenli Yang, Rajan Jain, Arjun Raj
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-022-02654-6