Bystander neuronal progenitors in forebrain organoids promote protective antiviral responses

Abstract Neurotropic viruses are the most common cause of infectious encephalitis and highly target neurons for infection. Our understanding of the intrinsic capacity of neuronal innate immune responses to mediate protective antiviral responses remains incomplete. Here, we evaluated the role of inte...

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Bibliographic Details
Main Authors: Seble G. Negatu, Christine Vazquez, Carl Bannerman, Kevin R. Amses, Guo-Li Ming, Kellie A. Jurado
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-025-03381-y