Hyperfibrinolysis: a crucial phenotypic abnormality of posttraumatic fibrinolytic dysfunction

Hyperfibrinolysis: a crucial phenotypic abnormality of posttraumatic fibrinolytic dysfunction

Background: Traumatic fibrinolytic dysfunction is often categorized into 3 phenotypes based on the result of thromboelastography (TEG) lysis at 30 minutes (LY30): fibrinolysis shutdown, physiologic fibrinolysis, and hyperfibrinolysis. However, the molecular pathophysiology of fibrinolytic dysfunctio...

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Bibliographic Details
Main Authors: Kyosuke Takahashi, Kazuma Yamakawa, Anaar E. Siletz, Morihiro Katsura, John B. Holcomb, Charles E. Wade, Jessica C. Cardenas, Erin E. Fox, Morgan Schellenberg, Matthew Martin, Kenji Inaba, Kazuhide Matsushima
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
blood transfusion
hyperfibrinolysis
outcome
thromboelastography
trauma-induced coagulopathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037924002632

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http://www.sciencedirect.com/science/article/pii/S2475037924002632

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