Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study
Background: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. Aim: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quan...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=2;spage=184;epage=190;aulast= |
| _version_ | 1828891115431919616 |
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| author | Yugal Kishor Sharma Pankaj Shukla Roopa Nayak Preeti Kothari Aayush Gupta |
| author_facet | Yugal Kishor Sharma Pankaj Shukla Roopa Nayak Preeti Kothari Aayush Gupta |
| author_sort | Yugal Kishor Sharma |
| collection | DOAJ |
| description | Background: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. Aim: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. Materials and Methods: Adult males, totaling 196, ascertained to fulfill the Royal College of Psychiatry criteria for chronic alcoholism by the de-addiction center and referred for dermatological consult were enrolled as cases, and similar number of age-/sex-matched teetotallers, as controls. Data emanating from detailed history, clinical examination, and routine liver functions tests were summarized and subsequently analyzed, including statistically using the Chi-square, independent “t” and Spearman's rank correlation tests, and compared with data from previous studies. Results: Majority (104) drank 41–50 units of alcohol/week since 3–40 (mean: 20.01 ± 9.322) years. Generalized pruritus (odds ratio [OR]: 31.15, P < 0.001), xerosis (OR: 3.62, P = 0.008), and seborrheic dermatitis (OR: 12.26, P < 0.001) were significantly more common in cases than controls. Infections (73; 37.2%), eczemas (45; 22.9%), and generalized hyperpigmentation (28; 14.2%) were the major presenting complaints. Spider nevi, gynecomastia, and pellagroid dermatitis were present in 34 (17.3%), 19 (9.7%), and 8 (4.1%) respectively exclusively in cases only. Commonly seen systemic abnormalities were an alcoholic liver disease (45; 22.9%), diabetes mellitus (23; 11.7%), and peripheral neuropathy (19; 9.7%). Conclusion: Knowledge of cutaneous manifestations of chronic alcoholism could prompt in-depth history taking of alcohol intake, lead to specialist referral and thereby enable timely de-addiction, hopefully before serious adversities in the chronic alcoholics. |
| first_indexed | 2024-12-13T13:11:25Z |
| format | Article |
| id | doaj.art-f4d3dc95f1a04e7dbcbb8a601b59648f |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-13T13:11:25Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-f4d3dc95f1a04e7dbcbb8a601b59648f2022-12-21T23:44:40ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112017-01-0162218419010.4103/ijd.IJD_348_16Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional studyYugal Kishor SharmaPankaj ShuklaRoopa NayakPreeti KothariAayush GuptaBackground: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. Aim: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. Materials and Methods: Adult males, totaling 196, ascertained to fulfill the Royal College of Psychiatry criteria for chronic alcoholism by the de-addiction center and referred for dermatological consult were enrolled as cases, and similar number of age-/sex-matched teetotallers, as controls. Data emanating from detailed history, clinical examination, and routine liver functions tests were summarized and subsequently analyzed, including statistically using the Chi-square, independent “t” and Spearman's rank correlation tests, and compared with data from previous studies. Results: Majority (104) drank 41–50 units of alcohol/week since 3–40 (mean: 20.01 ± 9.322) years. Generalized pruritus (odds ratio [OR]: 31.15, P < 0.001), xerosis (OR: 3.62, P = 0.008), and seborrheic dermatitis (OR: 12.26, P < 0.001) were significantly more common in cases than controls. Infections (73; 37.2%), eczemas (45; 22.9%), and generalized hyperpigmentation (28; 14.2%) were the major presenting complaints. Spider nevi, gynecomastia, and pellagroid dermatitis were present in 34 (17.3%), 19 (9.7%), and 8 (4.1%) respectively exclusively in cases only. Commonly seen systemic abnormalities were an alcoholic liver disease (45; 22.9%), diabetes mellitus (23; 11.7%), and peripheral neuropathy (19; 9.7%). Conclusion: Knowledge of cutaneous manifestations of chronic alcoholism could prompt in-depth history taking of alcohol intake, lead to specialist referral and thereby enable timely de-addiction, hopefully before serious adversities in the chronic alcoholics.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=2;spage=184;epage=190;aulast=Alcohol abusechronic alcoholicsliver damageskin manifestations |
| spellingShingle | Yugal Kishor Sharma Pankaj Shukla Roopa Nayak Preeti Kothari Aayush Gupta Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study Indian Journal of Dermatology Alcohol abuse chronic alcoholics liver damage skin manifestations |
| title | Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study |
| title_full | Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study |
| title_fullStr | Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study |
| title_full_unstemmed | Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study |
| title_short | Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study |
| title_sort | association of dermatoses with duration and quantum of alcohol intake a comparative cross sectional study |
| topic | Alcohol abuse chronic alcoholics liver damage skin manifestations |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=2;spage=184;epage=190;aulast= |
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