A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus.

Generally, the second messenger bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) regulates the switch between motile and sessile lifestyles in bacteria. Here, we show that c-di-GMP is an essential regulator of multicellular development in the social bacterium Myxococcus xanthus. In response to st...

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Bibliographic Details
Main Authors: Dorota Skotnicka, Gregory T Smaldone, Tobias Petters, Eleftheria Trampari, Jennifer Liang, Volkhard Kaever, Jacob G Malone, Mitchell Singer, Lotte Søgaard-Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4877007?pdf=render