Expansion of human bone marrow-derived mesenchymal stromal cells with enhanced immunomodulatory properties

Expansion of human bone marrow-derived mesenchymal stromal cells with enhanced immunomodulatory properties

Abstract Background Mesenchymal stromal cells (MSCs) have broad potential as a cell therapy including for the treatment of drug-resistant inflammatory conditions with abnormal T cell proliferation such as graft-versus-host disease (GVHD). Clinical success, however, has been complicated by the hetero...

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Bibliographic Details
Main Authors: Shu Hui Neo, Zhisheng Her, Rashidah Othman, Ching Ann Tee, Li Ching Ong, Yuehua Wang, Irwin Tan, Jaylen Tan, Yanmeng Yang, Zheng Yang, Qingfeng Chen, Laurie A. Boyer
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Immunomodulation
T cells
Cell culture
Confluency
Graft-versus-host disease
Online Access:https://doi.org/10.1186/s13287-023-03481-7

Internet

https://doi.org/10.1186/s13287-023-03481-7

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