Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models
A low level of tissue oxygen (hypoxia) is a physiological feature of a wide range of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydroxylase enzymes, which regulate the protein stability of hypoxia-inducible factor α (HIF-α) transcription factors. When stabilis...
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
The Company of Biologists
2015-11-01
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| श्रृंखला: | Disease Models & Mechanisms |
| विषय: | |
| ऑनलाइन पहुंच: | http://dmm.biologists.org/content/8/11/1349 |