A gene expression signature in HER2+ breast cancer patients related to neoadjuvant chemotherapy resistance, overall survival, and disease-free survival

Breast cancer ranks first in terms of mortality and incidence rates worldwide among women. The HER2+ molecular subtype is one of the most aggressive subtypes; its treatment includes neoadjuvant chemotherapy and the use of a HER2 antibody. Some patients develop resistance despite positive results obt...

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Bibliographic Details
Main Authors: Carlos A. Barrón-Gallardo, Mariel Garcia-Chagollán, Andres J. Morán-Mendoza, Raul Delgadillo-Cristerna, María G. Martínez-Silva, María M. Villaseñor-García, Adriana Aguilar-Lemarroy, Luis F. Jave-Suárez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.991706/full