Directed differentiation into insulin-producing cells using microRNA manipulation

Our commentary is focused on three studies that used microRNA overexpression methods for directed differentiation of stem cells into insulin-producing cells. Islet transplantation is the only cell-based therapy used to treat type 1 diabetes mellitus. However, due to the scarcity of cadaveric donors...

Full description

Bibliographic Details
Main Authors: Williams Michael D., Joglekar Mugdha V., Hardikar Anandwardhan A., Wong Wilson K. M.
Format: Article
Language:English
Published: De Gruyter 2020-06-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2020-0170