PPARγ induces growth inhibition and apoptosis through upregulation of insulin-like growth factor-binding protein-3 in gastric cancer cells

Peroxisome proliferator activator receptor-gamma (PPARγ) is a ligand-activated transcriptional factor involved in the carcinogenesis of various cancers. Insulin-like growth factor-binding protein-3 (IGFBP-3) is a tumor suppressor gene that has anti-apoptotic activity. The purpose of this study was t...

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Bibliographic Details
Main Authors: S.Y. Kim, M.S. Kim, M.K. Lee, J.S. Kim, H.K. Yi, S.Y. Nam, D.Y. Lee, P.H. Hwang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000300226&tlng=en