Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis
Abstract Background Plasmodium falciparum infections with slow parasite clearance following artemisinin-based therapies are widespread in the Greater Mekong Subregion. A molecular marker of the slow clearance phenotype has been identified: single genetic changes within the propeller region of the Ke...
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Format: | Article |
Language: | English |
Published: |
BMC
2019-01-01
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Series: | BMC Medicine |
Online Access: | http://link.springer.com/article/10.1186/s12916-018-1207-3 |