Protein alignment based on higher order conditional random fields for template-based modeling.

The query-template alignment of proteins is one of the most critical steps of template-based modeling methods used to predict the 3D structure of a query protein. This alignment can be interpreted as a temporal classification or structured prediction task and first order Conditional Random Fields ha...

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Bibliographic Details
Main Authors: Juan A Morales-Cordovilla, Victoria Sanchez, Martin Ratajczak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5983487?pdf=render