Helicobacter pylori and cagA gene detected by polymerase chain reaction in gastric biopsies: correlation with histological findings, proliferation and apoptosis

Helicobacter pylori and cagA gene detected by polymerase chain reaction in gastric biopsies: correlation with histological findings, proliferation and apoptosis

CONTEXT AND OBJECTIVE: The virulence of Helicobacter pylori (HP) in gastroduodenal disease is related to pathogenicity islands (cagPAI) present in some strains. Infection with cagPAI induces IL-8 secretion, increases epithelial cell proliferation and may be important in carcinogenesis. Our objective...

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Bibliographic Details
Main Authors: Katia Ramos Moreira Leite, Elaine Darini, Flavio Canelas Canavez, Claudia Muraro de Carvalho, Cristina Aparecida Troquez da Silveira Mitteldorf, Luiz Heraldo Camara-Lopes
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Helicobacter pylori
Pathogenicity island
Polymerase chain reaction
Immunohistochemistry
Apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802005000300005&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802005000300005&lng=en&tlng=en

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