Aliskiren reduces prorenin receptor expression and activity in cultured human aortic smooth muscle cells
Introduction : The recent discovery of a specific receptor for renin/prorenin (PRR) has added new interest to the potential pharmacological actions of aliskiren, the first direct renin inhibitor. Materials and methods : In the present study, to gain new insights into the pharmacological properties o...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2011-12-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/1470320311408751 |