Aliskiren reduces prorenin receptor expression and activity in cultured human aortic smooth muscle cells

Introduction : The recent discovery of a specific receptor for renin/prorenin (PRR) has added new interest to the potential pharmacological actions of aliskiren, the first direct renin inhibitor. Materials and methods : In the present study, to gain new insights into the pharmacological properties o...

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Bibliographic Details
Main Authors: Nicola Ferri, Carolina Magdalen Greco, Giuseppe Maiocchi, Alberto Corsini
Format: Article
Language:English
Published: SAGE Publications 2011-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311408751

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