A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors

A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors

Rabies virus (RABV) causes severe neurological symptoms in mammals. The disease is almost inevitably lethal as soon as clinical symptoms appear. The use of rabies immunoglobulins (RIG) and vaccination in post-exposure prophylaxis (PEP) can provide efficient protection, but many people do not receive...

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Bibliographic Details
Main Authors: Xinyu Wang, Winston Chiu, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Johan Neyts, Dirk Jochmans
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Viruses
Subjects:
rabies virus
high-throughput screening
drug repurposing
antiviral therapy
Online Access:https://www.mdpi.com/1999-4915/15/12/2292

Internet

https://www.mdpi.com/1999-4915/15/12/2292

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