A dual computational and experimental strategy to enhance TSLP antibody affinity for improved asthma treatment.
Thymic stromal lymphopoietin is a key cytokine involved in the pathogenesis of asthma and other allergic diseases. Targeting TSLP and its signaling pathways is increasingly recognized as an effective strategy for asthma treatment. This study focused on enhancing the affinity of the T6 antibody, whic...
| Główni autorzy: | , , , , , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
Public Library of Science (PLoS)
2024-03-01
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| Seria: | PLoS Computational Biology |
| Dostęp online: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011984&type=printable |