Fluoxetine Protects Retinal Ischemic Damage in Mice

Fluoxetine Protects Retinal Ischemic Damage in Mice

Background: To evaluate the neuroprotective effect of the topical ocular administration of fluoxetine (FLX) in a mouse model of acute retinal damage. Methods: Ocular ischemia/reperfusion (I/R) injury in C57BL/6J mice was used to elicit retinal damage. Mice were divided into three groups: control gro...

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Bibliographic Details
Main Authors: Giovanni Luca Romano, Lucia Gozzo, Oriana Maria Maurel, Serena Di Martino, Valentina Riolo, Vincenzo Micale, Filippo Drago, Claudio Bucolo
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
neuroprotection
retinal ganglion cells
ischemia reperfusion
fluoxetine
Online Access:https://www.mdpi.com/1999-4923/15/5/1370

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https://www.mdpi.com/1999-4923/15/5/1370

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