Chimeric ZHHH neuroglobin acts as a cell membrane‐penetrating inducer of neurite outgrowth

Neuroglobin (Ngb) is a heme protein expressed in the vertebrate brain. We previously engineered a chimeric Ngb protein, in which module M1 of human Ngb is replaced by that of zebrafish Ngb, and showed that the chimeric ZHHH Ngb has a cell membrane‐penetrating activity similar to that of zebrafish Ng...

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Bibliographic Details
Main Authors: Nozomu Takahashi, Wataru Onozuka, Seiji Watanabe, Keisuke Wakasugi
Format: Article
Language:English
Published: Wiley 2017-09-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12271