Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth

Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth

Glioblastoma (GBM) is a malignant brain tumor. The purpose of this study is to estimate the potential effects and underlying mechanisms of a ubiquitin-specific protease 8 (USP8) small-molecule inhibitor on the phenotypic characteristics of GBM cells. The growth, migration, invasion, and stemness of...

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Bibliographic Details
Main Authors: Long Yu, Hu Zengchun, Yang Dian, Wang Fuqiang, Zhao Chen’ge, Zhang Yang, Zhang Yingqiu, Ma Hui, Lv Huiyi
Format: Article
Language:English
Published: De Gruyter 2023-02-01
Series:Open Life Sciences
Subjects:
gbm
aurka
usp8
small molecule inhibitor
Online Access:https://doi.org/10.1515/biol-2022-0562

Internet

https://doi.org/10.1515/biol-2022-0562

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