Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability

Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability

Abstract Background Decapping of mRNA is an important step in the regulation of mRNA turnover and therefore of gene expression, which is a key process controlling development and homeostasis of all organisms. It has been shown that EDC3 plays a role in mRNA decapping, however its function is not wel...

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Autori principali: Ute Scheller, Kathrin Pfisterer, Steffen Uebe, Arif B. Ekici, André Reis, Rami Jamra, Fulvia Ferrazzi
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2018-04-01
Serie:BMC Medical Genomics
Soggetti:
EDC3
mRNA degradation
Intellectual disability
Transcriptome analysis
Pathways
Co-expression network
Accesso online:http://link.springer.com/article/10.1186/s12920-018-0358-6

Accesso online

http://link.springer.com/article/10.1186/s12920-018-0358-6

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