Higher Mutation Burden in High Proliferation Compartments of Heterogeneous Melanoma Tumors

Higher Mutation Burden in High Proliferation Compartments of Heterogeneous Melanoma Tumors

Melanoma tumors are the most heterogeneous of all tumor types. Tumor heterogeneity results in difficulties in diagnosis and is a frequent cause of failure in treatment. Novel techniques enable accurate examination of the tumor cells, considering their heterogeneity. The study aimed to determine the...

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Bibliographic Details
Main Authors: Tomasz M. Grzywa, Agnieszka A. Koppolu, Wiktor Paskal, Klaudia Klicka, Małgorzata Rydzanicz, Jarosław Wejman, Rafał Płoski, Paweł K. Włodarski
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
intratumor heterogeneity
genetic heterogeneity
melanoma
NGS
Online Access:https://www.mdpi.com/1422-0067/22/8/3886

Internet

https://www.mdpi.com/1422-0067/22/8/3886

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