Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis

Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis

IntroductionAppendicitis is one of the most common causes of acute abdominal surgery in children. The clinical course of appendicitis ranges from simple to complex appendicitis. The mechanisms underlying the heterogeneity of appendicitis in children remain largely unclear. Dysregulated T cell respon...

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Bibliographic Details
Main Authors: Sarah-May M. L. The, Renée R. C. E. Schreurs, Agata Drewniak, Roel Bakx, Tim G. J. de Meij, Andries E. Budding, Linda Poort, Huib A. Cense, Hugo A. Heij, L. W. Ernest van Heurn, Ramon R. Gorter, Madeleine J. Bunders
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
appendicitis
children
T cells
Th17
microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258363/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258363/full

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