Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma

Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality, and despite recent advances in early diagnosis and therapeutics, HCC related morbidity and mortality rate continue to rise. Clearly, it is imperative to develop novel effective therapies for HCC to improve lon...

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Bibliographic Details
Main Authors: Sumit Siddharth, Nethaji Muniraj, Neeraj K. Saxena, Dipali Sharma
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
hepatocellular carcinoma
LC3B
cytoprotective autophagy
cathepsin-D
withaferin A
Online Access:https://www.mdpi.com/2072-6694/11/4/453

Internet

https://www.mdpi.com/2072-6694/11/4/453

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