Sestrin2/Keap1/Nrf2 pathway regulates mucus hypersecretion in pulmonary epithelium induced by traffic-related PM2.5 and water-soluble extracts

The involvement of fine particulate matter (PM2.5) exposure in the progression of asthma has been extensively discussed in epidemiological and experimental evidence, which aroused widespread attention. Asthma is characterized by mucus hypersecretion. This study investigates the underlying toxic mech...

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Bibliographic Details
Main Authors: Jiayu Tian, Xin Wang, Hao Shi, Hongyan Wu, Caihong Wang, Nannan Liu, Linlin Guan, Zhihong Zhang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323009594