An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA
Chemical damage to RNA affects its functional properties and thus may pose a significant hurdle to the translational apparatus; however, the effects of damaged mRNA on the speed and accuracy of the decoding process and their interplay with quality-control processes are not known. Here, we systematic...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-11-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714009115 |