Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer

Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and leads to the poorest patient outcomes despite surgery and chemotherapy treatment. Exploring new molecular mechanisms of TNBC that could lead to the development of novel molecular targets are cri...

Full description

Bibliographic Details
Main Authors: Zheqiong Tan, Pragney Deme, Keerti Boyapati, Britt S. R. Claes, Annet A. M. Duivenvoorden, Ron M. A. Heeren, Caitlin M. Tressler, Norman James Haughey, Kristine Glunde
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Breast Cancer Research
Subjects:
PNPLA8
Breast cancer
Triple negative
Phospholipid
Metabolism reprogramming
Eicosanoids
Online Access:https://doi.org/10.1186/s13058-023-01742-0

Internet

https://doi.org/10.1186/s13058-023-01742-0

Similar Items