Circulating Plasma Proteins in Aortic Stenosis: Associations With Severity, Myocardial Response, and Clinical Outcomes

Circulating Plasma Proteins in Aortic Stenosis: Associations With Severity, Myocardial Response, and Clinical Outcomes

Background Echocardiographic indexes of aortic stenosis may not comprehensively reflect disease morbidity. Plasma proteomic profiling may add prognostic value in these patients. Methods and Results Proximity extension assays (Olink) of 183 circulating cardiovascular and inflammatory proteins were pe...

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Bibliographic Details
Main Authors: Eugene S. J. Tan, Hyungwon Choi, Christopher R. DeFilippi, Yen‐Yee Oon, Siew‐Pang Chan, Lingli Gong, Josephine B. Lunaria, Oi‐Wah Liew, Jenny Pek‐Ching Chong, Edgar Lik‐Wui Tay, Wern‐Miin Soo, James Wei‐Luen Yip, Quek Wei Yong, Evelyn Min Lee, Poh Shuan Daniel Yeo, Zee Pin Ding, Hak Chiaw Tang, See Hooi Ewe, Calvin W. L. Chin, Siang Chew Chai, Ping Ping Goh, Lee Fong Ling, Hean Yee Ong, A. Mark Richards, Lieng‐Hsi Ling
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aortic stenosis
biomarkers
inflammation
proteomics
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.035486

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https://www.ahajournals.org/doi/10.1161/JAHA.124.035486

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