Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery

Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery

Abstract Background Crosstalk between the aryl hydrocarbon receptor (AhR) and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling is called the “AhR–Nrf2 gene battery”, which works synergistically in detoxification to support cell survival. Nrf2-dependent phase II gene promoters are control...

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Bibliographic Details
Main Authors: Kenly Wuputra, Ming-Ho Tsai, Kohsuke Kato, Chia-Chen Ku, Jia-Bin Pan, Ya-Han Yang, Shigeo Saito, Chun-Chieh Wu, Ying-Chu Lin, Kuang-Hung Cheng, Kung-Kai Kuo, Michiya Noguchi, Yukio Nakamura, Tohru Yoshioka, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K. Yokoyama
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Inflammation and Regeneration
Subjects:
Antioxidation
Aryl hydrocarbon receptor
Dioxin responsive element
Nuclear factor (erythroid-derived 2)-like 2 transcription factor
Jun dimerization protein 2
Oxidative stress
Online Access:https://doi.org/10.1186/s41232-023-00290-6

Internet

https://doi.org/10.1186/s41232-023-00290-6

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