The mitochondrial biliverdin exporter ABCB10 in hepatocytes mitigates neutrophilic inflammation in alcoholic hepatitis

Acute liver failure caused by alcoholic hepatitis (AH) is only effectively treated with liver transplantation. Livers of patients with AH show a unique molecular signature characterized by defective hepatocellular redox metabolism, concurrent to hepatic infiltration of neutrophils that express myelo...

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Bibliographic Details
Main Authors: Vincent Gutierrez, Doyeon Kim-Vasquez, Michael Shum, Qihong Yang, Dante Dikeman, Stan G. Louie, Orian S. Shirihai, Hidekazu Tsukamoto, Marc Liesa
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000284