Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal Cancer

Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal Cancer

Fibroblasts constitute a ubiquitous mesenchymal cell type and produce the extracellular matrix (ECM) of connective tissue, thereby providing the structural basis of various organs. Fibroblasts display differential transcriptional patterns unique to the organ of their origin and they can be activated...

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Bibliographic Details
Main Authors: Naoya Miyashita, Akira Saito
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
cancer-associated fibroblast
colorectal cancer
TGF-β
PDGF
FOXL1
Online Access:https://www.mdpi.com/1422-0067/22/20/10973

Internet

https://www.mdpi.com/1422-0067/22/20/10973

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