Profiling gut microbiota and bile acid metabolism in critically ill children

Profiling gut microbiota and bile acid metabolism in critically ill children

Abstract Broad-spectrum antimicrobial use during the treatment of critical illness influences gastrointestinal fermentation endpoints, host immune response and metabolic activity including the conversion of primary to secondary bile acids. We previously observed reduced fermentation capacity in the...

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Bibliographic Details
Main Authors: Iain Robert Louis Kean, Joseph Wagner, Anisha Wijeyesekera, Marcus De Goffau, Sarah Thurston, John A. Clark, Deborah K. White, Jenna Ridout, Shruti Agrawal, Riaz Kayani, Roddy O’Donnell, Padmanabhan Ramnarayan, Mark J. Peters, Nigel Klein, Elaine Holmes, Julian Parkhill, Stephen Baker, Nazima Pathan
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13640-0

Internet

https://doi.org/10.1038/s41598-022-13640-0

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