Biomarkers of NRF2 signalling: Current status and future challenges

Biomarkers of NRF2 signalling: Current status and future challenges

The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a number of diseases associated with oxidative stress and inflammation. Hence, an ability to monitor basal and inducible NRF2 signalling is vital...

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Bibliographic Details
Main Authors: Christina Morgenstern, Isabel Lastres-Becker, Birsen Can Demirdöğen, Vera Marisa Costa, Andreas Daiber, Roberta Foresti, Roberto Motterlini, Sibel Kalyoncu, Burak I. Arioz, Sermin Genc, Monika Jakubowska, Ioannis P. Trougakos, Aleksandra Piechota-Polanczyk, Michel Mickael, Marlene Santos, Thomas W. Kensler, Antonio Cuadrado, Ian M. Copple
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Redox Biology
Subjects:
NRF2
Transcription factor
Target genes
Biomarker
Oxidative stress response
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724001101

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http://www.sciencedirect.com/science/article/pii/S2213231724001101

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