PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair

PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair

Abstract Background Endometrial cancer (EC) arises from uterine endometrium tissue and is the most prevalent cancer of the female reproductive tract in developed countries. It has been predicted that the global prevalence of EC will increase in part because of its positive association with economic...

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Bibliographic Details
Main Authors: Fathima Hameed J S, Anjali Devarajan, Devu Priya M S, Ahel Bhattacharyya, Mayur Balkrishna Shirude, Debasree Dutta, Parimal Karmakar, Ananda Mukherjee
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Endometrial cancer
PTEN
DDB2
DNA damage response
Nucleotide excision repair
Unscheduled DNA synthesis
Online Access:https://doi.org/10.1186/s12885-023-10892-5

Internet

https://doi.org/10.1186/s12885-023-10892-5

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