Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers

The overexpression of survivin is usually accompanied by an increased resistance of cancer cells to chemotherapeutic agents in addition to cancer aggressiveness. Consequently, survivin is considered as an attractive target to develop new promising anticancer candidates. A series of novel 3-cyanopyri...

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Bibliographic Details
Main Authors: Rehab Sabour, Marwa F. Harras, Omkulthom Mohamed Al Kamaly, Najla Altwaijry
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/21/4892