Electrical stimulus artifact cancellation and neural spike detection on large multi-electrode arrays.

Simultaneous electrical stimulation and recording using multi-electrode arrays can provide a valuable technique for studying circuit connectivity and engineering neural interfaces. However, interpreting these measurements is challenging because the spike sorting process (identifying and segregating...

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Bibliographic Details
Main Authors: Gonzalo E Mena, Lauren E Grosberg, Sasidhar Madugula, Paweł Hottowy, Alan Litke, John Cunningham, E J Chichilnisky, Liam Paninski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5703587?pdf=render