Nanoscale organization of the endogenous ASC speck

Nanoscale organization of the endogenous ASC speck

Summary: The NLRP3 inflammasome is a central component of the innate immune system. Its activation leads to formation of the ASC speck, a supramolecular assembly of the inflammasome adaptor protein ASC. Different models, based on ASC overexpression, have been proposed for the structure of the ASC sp...

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Bibliographic Details
Main Authors: Ivo M. Glück, Grusha Primal Mathias, Sebastian Strauss, Virgile Rat, Irene Gialdini, Thomas Sebastian Ebert, Che Stafford, Ganesh Agam, Suliana Manley, Veit Hornung, Ralf Jungmann, Christian Sieben, Don C. Lamb
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Immunology
Biotechnology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223024598

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223024598

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