Overexpression of c-myc and loss of heterozigosity on 2p, 3p, 5q, 17p and 18q in sporadic colorectal carcinoma Sobreexpresión de c-myc y pérdida de heterozigosidad en 2p, 3p, 5q, 17p y 18q en carcinoma colorrectal esporádico

Overexpression of c-myc and loss of heterozigosity on 2p, 3p, 5q, 17p and 18q in sporadic colorectal carcinoma Sobreexpresión de c-myc y pérdida de heterozigosidad en 2p, 3p, 5q, 17p y 18q en carcinoma colorrectal esporádico

Aim: the aim of the present study is to evaluate the prognostic influence of loss of heterozygosity on 2p, 3p, 5q, 17p and 18q, and c-myc overexpression on surgically treated sporadic colorectal carcinoma. Methods: tumor and non-tumor tissue samples from 153 patients were analyzed. Fifty-one percent...

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Bibliographic Details
Main Authors: A. Sánchez-Pernaute, E. Pérez-Aguirre, F.J. Cerdán, P. Iniesta, L. Díez Valladares, C. de Juan, A. Morán, A. García-Botella, C. García Aranda, M. Benito, A.J. Torres, J.L. Balibrea
Format: Article
Language:English
Published: Aran Ediciones 2005-03-01
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
Pérdida de heterozigosidad
c-myc
Oncogenes
Pronóstico
Carcinoma colorrectal
Loss of heterozygosity
Prognosis
Colorectal carcinoma
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082005000300005

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