Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced psoriasis-like skin lesions

Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced psoriasis-like skin lesions

Psoriasis is a chronic inflammatory skin disease characterized by thickening the epidermis with erythema, scaling, and proliferation. Noscapine (NOS) has several anti-inflammatory, anti-angiogenic, and anti-fibrotic effects, but its low solubility and large size results in its lower efficacy in the...

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Bibliographic Details
Main Authors: Pouria Rahmanian-Devin, Vahid Reza Askari, Zahra Sanei-Far, Vafa Baradaran Rahimi, Hossein Kamali, Mahmoud Reza Jaafari, Shiva Golmohammadzadeh
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Noscapine
SLN
Chronic Inflammation
Psoriasis
Topical treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016219

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http://www.sciencedirect.com/science/article/pii/S0753332223016219

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