ROLE OF HLA ADAPTATION IN HIV EVOLUTION
Killing of HIV-infected cells by CD8+ T-cells imposes strong selection pressure on the virus towards escape. The HLA class I molecules that are successful in mediating some degree of control over the virus are those that tend to present epitopes in conserved regions of the proteome, such as in p24 G...
| Hoofdauteurs: | , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Frontiers Media S.A.
2016-01-01
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| Reeks: | Frontiers in Immunology |
| Onderwerpen: | |
| Online toegang: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00665/full |