Senescent epithelial cells remodel the microenvironment for the progression of oral submucous fibrosis through secreting TGF-β1
Objectives Cellular senescence is strongly associated with fibrosis and tumorigenesis. However, whether the epithelium of oral submucous fibrosis (OSF) undergoes premature senescence remains unclear. This study investigates the roles of senescent epithelial cells in OSF. Methods The immunohistochemi...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2023-04-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/15158.pdf |