Senescent epithelial cells remodel the microenvironment for the progression of oral submucous fibrosis through secreting TGF-β1
Objectives Cellular senescence is strongly associated with fibrosis and tumorigenesis. However, whether the epithelium of oral submucous fibrosis (OSF) undergoes premature senescence remains unclear. This study investigates the roles of senescent epithelial cells in OSF. Methods The immunohistochemi...
Main Authors: | Zijia Wang, Ying Han, Ying Peng, Shuhui Shao, Huanquan Nie, Kun Xia, Haofeng Xiong, Tong Su |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2023-04-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/15158.pdf |
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