Solanimycin: Biosynthesis and Distribution of a New Antifungal Antibiotic Regulated by Two Quorum-Sensing Systems

Solanimycin: Biosynthesis and Distribution of a New Antifungal Antibiotic Regulated by Two Quorum-Sensing Systems

ABSTRACT The increasing emergence of drug-resistant fungal infections has necessitated a search for new compounds capable of combating fungal pathogens of plants, animals, and humans. Microorganisms represent the main source of antibiotics with applicability in agriculture and in the clinic, but man...

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Bibliographic Details
Main Authors: Miguel A. Matilla, Rita E. Monson, Annabel Murphy, Muriel Schicketanz, Alison Rawlinson, Caia Duncan, Juan Mata, Finian Leeper, George P. C. Salmond
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
Dickeya solani
acyl-homoserine lactone
agriculture and global food security
antibiotics
antifungal agents
gene regulation
Online Access:https://journals.asm.org/doi/10.1128/mbio.02472-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02472-22

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