The Involvement of ALPK3 in Hypertrophic Cardiomyopathy in East Asia

The Involvement of ALPK3 in Hypertrophic Cardiomyopathy in East Asia

ObjectiveALPK3 is associated with a recessive form of pediatric cardiomyopathy accompanied by musculoskeletal and craniofacial abnormalities. Heterozygous truncating variants in this gene (ALPK3tv) have recently been confirmed as a cause of autosomal dominant hypertrophic cardiomyopathy (HCM). Wheth...

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Bibliographic Details
Main Authors: Jiaqi Dai, Ke Li, Man Huang, Yang Sun, Hao Liu, Zongzhe Li, Peng Chen, Hong Wang, Dongyang Wu, Yanghui Chen, Lei Xiao, Haoran Wei, Rui Li, Liyuan Peng, Ting Yu, Yan Wang, Dao Wen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
Subjects:
hypertrophic cardiomyopathy
East Asians
ALPK3
heterozygote
missense variant
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.915649/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.915649/full

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