Unique molecular features and cellular responses differentiate two populations of motor cortical layer 5b neurons in a preclinical model of ALS

Unique molecular features and cellular responses differentiate two populations of motor cortical layer 5b neurons in a preclinical model of ALS

Summary: Many neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), lead to the selective degeneration of discrete cell types in the CNS despite the ubiquitous expression of many genes linked to disease. Therapeutic advancement depends on understanding the unique cellular adaptati...

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Bibliographic Details
Main Authors: Maria V. Moya, Rachel D. Kim, Meghana N. Rao, Bianca A. Cotto, Sarah B. Pickett, Caroline E. Sferrazza, Nathaniel Heintz, Eric F. Schmidt
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472200300X

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http://www.sciencedirect.com/science/article/pii/S221112472200300X

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