Cyclin and DNA distributed cell cycle model for GS-NS0 cells.

Mammalian cell cultures are intrinsically heterogeneous at different scales (molecular to bioreactor). The cell cycle is at the centre of capturing heterogeneity since it plays a critical role in the growth, death, and productivity of mammalian cell cultures. Current cell cycle models use biological...

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Bibliographic Details
Main Authors: David G García Münzer, Margaritis Kostoglou, Michael C Georgiadis, Efstratios N Pistikopoulos, Athanasios Mantalaris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004062&type=printable